INFECT Logo

INterface For Empricial antimicrobial ChemoTherapy

See INFECT in action!

Project

The INFECT Project

Empirical antimicrobial therapy is a vital and widely applied concept in clinical medicine that relies on the availability of local antimicrobial resistance data and evidence-based guidelines. To support the availability of such data, the INFECT association initiated the open-source project INFECT (INterface For Empirical antimicrobial ChemoTherapy), aimed at informing and assisting clinicians with empirical antimicrobial treatments.

INFECT is a web application that works with all major internet browsers. The data source for INFECT is anonymized individual patient susceptibility data from the Swiss Center for Antibiotic Resistance (anresis.ch). In a monthly interval, INFECT automatically imports resistance information of the past 12 months, which is aggregated and shown in a substance-by-organism matrix, where the data can be filtered by multiple characteristics.

In order to handle the heavy computational load of combining filters that currently handle around 4 million data points on the fly, we have developed a distributed real-time in-memory analytics engine (the INFECT Processor) that can distribute load to multiple servers. To enhance the clinical usability of INFECT, a guideline module has been added that combines third-party empirical antimicrobial treatment guidelines (e.g., Swiss national treatment guidelines) with the regional resistance data.

The data can be filtered by users according to microbial (e.g., Gram stain), antimicrobial (e.g., substance class) or population (e.g., region, age) properties. Susceptibility is displayed as percentage in a coloured circle, with the circle colour showing the proportion of susceptibles while the circle size represents sample size:

INFECT explanation

With the INFECT application it is now possible to routinely assist empirical antimicrobial therapies with state-of-the-art information technology using the latest epidemiological data and third party guidelines. Due to its flexible modular design, INFECT may be adjusted to other data sources, or extended with further modules as needed.

The Swiss INFECT platforms are available on infect.info (data from human samples) and vet.infect.info (veterinary data).

In order to make the resistance data displayed in the INFECT application available to more users, the INFECT association has developed a web-based integrator platform that allows organizations to integrate the INFECT resistance matrix as a widget into their own web based medical treatment guidelines. The integrator platform is available at integration.infect.info and is free of charge.

Association

The INFECT Association

The INFECT application is designed, developed and operated by INFECT, a non-profit association under Swiss law, founded in 2016 and located in Bern, Switzerland.


The INFECT board is currently formed by (alphabetical order):

  • Prof. Silvio D. Brugger, MD, PhD; Head of Hospital Epidemiology Laboratory and Attending Physician at the Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Switzerland; INFECT founding member
  • Pascal M. Frey, MD, MSc; attending physician at the Department of General Internal Medicine, Bern University Hospital (Inselspital), Switzerland; INFECT founding member and current president
  • Philipp Jent, MD; Head of Infection Prevention and Control at the Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland
  • Lina van der Weg, Technological lead at the INFECT Association and Founder Rainbow Labs, Switzerland; INFECT founding member


INFECT active members actively contribute to forming the INFECT association by electing the board and steering committee. They are also our valuable beta testers and consist of (alphabetical order):

  • Sascha Albrecht, MD; Infectious Diseases Fellow at the Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland
  • Tobias Anliker, MD; Attending Physician at the Department of General Internal Medicine, Bern University Hospital, University of Bern, Bern, Switzerland, Board Member Swiss Young Internists
  • Prof. Drahomir Aujesky, MD, MSc; Director and Chief Physician of the Department of General Internal Medicine, Bern University Hospital, University of Bern, Bern, Switzerland; Co-President of the Swiss Society of General Internal Medicine (SSGIM)
  • PD Manuel Blum, MD, MSc; Senior Attending Physician at the Department of General Internal Medicine, Bern University Hospital, University of Bern, Bern, Switzerland
  • Philipp K. Bühler, MD; Head of the Centre for Intensive Care, Kantonsspital Winterthur, Switzerland
  • Michael Greiner, MD; Medical Microbiology Fellow at the Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland
  • Prof. Stefan Kuster, MD, MSc, EMBA UZH; Chief Physician of the Department of Infectious Diseases and Hospital Epidemiology, Kantonsspital St. Gallen, St. Gallen, Switzerland
  • Prof. Roger Kouyos, PhD; Head of Kouyos Lab at the Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland
  • Yonas Martin, MD; Infectious Diseases Fellow at the Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland
  • Prof. Nicolas Müller, MD; Senior Attending Physician at the Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland; Head of Transplantation Center, University Hospital Zurich; Board Member and Past President of the Society for Infectious Diseases (SSI)
  • Martin Perrig, MD, MME; Chief Physician at the Department of Internal Medicine, Bern University Hospital, University of Bern, Bern, Switzerland
  • Caroline Rimensberger, MD; Attending Physician at the Department of General Internal Medicine, Bern University Hospital, University of Bern, Bern, Switzerland; Board Member Swiss Young Internists
  • Thomas Scheier, MD; Research Fellow at the Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland; Attending Physician at the Department of Internal Medicine, Cantonal Hospital Schafhausen
  • Claudio Schneider, MD; Attending Physician at the Department of General Internal Medicine, Bern University Hospital, University of Bern, Bern, Switzerland
  • PD Tobias Tritschler, MD, MSc; Senior Attending Physician at the Department of General Internal Medicine, Bern University Hospital, University of Bern, Bern, Switzerland; President Swiss Young Internists


INFECT passive members ideologically and financially support our cause on a continuous basis (alphabetical order):

  • PD Markus Hilty, PhD, Institute for Infectious Diseases, University of Bern, Bern, Switzerland
  • PD Johannes Nemeth, MD; Attending Physician at the Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland


The INFECT steering committee is formed by (alphabetical order):

  • Prof. Silvio D. Brugger, MD, PhD; Head of Hospital Epidemiology Laboratory and Attending Physician at the Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Switzerland; INFECT founding member
  • Pascal M. Frey, MD, MSc; attending physician at the Department of General Internal Medicine, Bern University Hospital (Inselspital), Switzerland; INFECT founding member and current president
  • Philipp Jent, MD; Head of Infection Prevention and Control at the Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland
  • Prof. Stefan Kuster, MD, MSc, EMBA UZH; Chief Physician of the Department of Infectious Diseases and Hospital Epidemiology, Kantonsspital St. Gallen, St. Gallen, Switzerland
  • Lina van der Weg, Technological lead at the INFECT Association and Founder Rainbow Labs, Switzerland; INFECT founding member

The INFECT board and steering committee members are elected at the Annual General Meeting.

Donations

Donations are very welcome. The INFECT association is a non-profit organization and needs your support to continue its mission.

Your donation will be used to

  • support the operations of the infect association
  • develop new features for the infect framework
  • maintain the infect framework


One time donations

Membership

About the Membership

As of 2022 the INFECT association is accepting new members. All new members will receive the membership status of a “passive membership” without a right to vote at the Annual General Meeting. However, active membership including the right to vote can be granted by the INFECT board upon request.

In order to become a member, you have to subscribe to the INFECT association’s membership fee. The membership fee is CHF 100 per year. The membership fee can be paid by credit card or bank transfer using our online payment system. You may decide afterwards if you'd like to be listed as a member of the INFECT association on this website.


If you wish to upgrade your membership status to active membership, you need to contact us by email or by using the contact form below. You have to subscribe as a passive member to be eligible for active membership.

Contact

Let's have a conversation! Drop a message hello@infect.org
Send us a message
Thank you for contacting us! Postal address

INFECT Association
℅ Dr. med. Pascal Frey, Department of General Internal Medicine
Bern University Hospital, Inselspital
3010 Bern